4221 DEMEDICI Avenue, Jacksonville, FL 32210

• 4 beds |
• 3 baths |
• 1,891 sqft

Property Description

Welcome to this beautifully renovated home tucked in the heart of Jacksonville's beloved Venetia neighborhood--where timeless character meets thoughtful modern living. Originally built in 1941, this 4-bedroom, 3-bath residence blends warmth, charm, and extensive updates throughout. From the inviting front porch to the rich walnut hardwood floors, every space feels both comfortable and elevated. The thoughtfully updated interior features a renovated kitchen, bathrooms, and laundry space, creating a move-in-ready experience while still honoring the home's original character. The overall layout offers flexibility for both everyday living and entertaining, with spacious bedrooms, beautifully updated baths, and natural light throughout. Every detail reflects pride of ownership and intentional care. The bedroom layout offers both comfort and functionality, with three bedrooms thoughtfully situated on one side of the home. The bedroom layout offers both comfort and functionality, with three bedrooms thoughtfully situated on one side of the home. Two bedrooms share a beautifully updated bath, while the third features its own private en suite--creating an ideal setup for guests or multigenerational living. The primary suite is a true private retreat, featuring a spacious bedroom, dual closets, and a well-appointed bath complete with dual vanities and a stunning oversized shower. Thoughtfully designed for both comfort and relaxation, the suite also offers direct access to the incredible backyard oasis. The built-in fire pit and outdoor kitchen create the ultimate entertaining space--perfect for gathering with family and friends year-round. Privacy, functionality, and effortless outdoor living come together beautifully to make this backyard an extension of the home for all to enjoy. Outside, enjoy the charm of one of Jacksonville's most sought-after historic pockets, known for its tree-lined streets, strong sense of community, and proximity to the river, local parks, dining, and shopping. The fenced backyard and inviting outdoor space offer room to relax, entertain, and truly feel at home. Newer windows, updated HVAC and ductwork, and major system improvements--including crawl space encapsulation with drainage system, dehumidifier, and pump--provide peace of mind and long-term functionality. This is the kind of home that rarely comes available in Venetia--full of charm, beautifully improved, and ready for its next chapter

Listing Status:

Active

Date Added:

May 9, 2026

Data Last Updated:

May 11, 2026 at 8:37PM

Listing Office:

ROOT REALTY LLC : 904-612-5477

Listing Agent:

MaryAnne Rodriguez : 904-814-0022

MLS ID:

2144416

Interior

• General: Ceiling Fan(s)His and Hers ClosetsPantryPrimary DownstairsVaulted Ceiling(s)Primary Bathroom - Shower No TubSplit BedroomsGuest Suite
• Appliances: DryerDisposalDishwasherElectric RangeElectric Water HeaterMicrowaveRefrigeratorWasher
• Laundry: Electric Dryer HookupLower LevelIn UnitWasher Hookup
• Flooring: TileWood
• A/C: Central Air
• Heating:
• Fireplace: Wood BurningFireplaceFireplaces: 1

Exterior

• General: Fire PitOutdoor KitchenOutdoor Kitchen
• Style: Traditional

Construction

• Roofing: Shingle
• General: 1

Location

• Road/Access: City Street
• Originating MLS: realMLS (Northeast Florida Multiple Listing Service)
• County: Duval

Lot

• Zoning: 1026630000
• Current Use: ResidentialSingle Family

Utilities

• Utilities: Electricity ConnectedSewer ConnectedWater Connected
• Water: Public
• Sewer: Public Sewer

Financial

• Source: realMLS (Northeast Florida Multiple Listing Service)