4444 Main Street, Amherst, NY 14226

• 3,641 sqft

Property Description

Exceptional 5-Unit Commercial Investment | Prime Main Street Location A rare and highly desirable investment opportunity in one of Western New York’s most sought-after corridors. Perfectly positioned on Main Street between Williamsville and the University at Buffalo South Campus, this fully renovated mixed-use commercial property offers unmatched visibility, versatility, and income potential. Completely updated from top to bottom, the building features five distinct income-producing units, making it an ideal asset for investors seeking strong cash flow or owner-operators looking to offset occupancy costs while building long-term equity. The lower level offers two well-designed office suites: The front unit features a spacious main area complemented by a private office or waiting room. The rear unit includes a large open workspace, two private offices, and an optional additional room—ideal for flexible configurations. The first floor showcases two unique commercial spaces: A highly visible front unit, formerly a tattoo studio, boasts large windows, its own private entrance, and multiple additional rooms—perfect for retail, barbershop, salon, or boutique business use. The rear unit offers a wide-open layout with a welcoming front reception area and was previously utilized as a yoga studio—ideal for fitness, wellness, or studio-based businesses. The second floor features an impressive executive office suite complete with a central hallway, multiple private offices, a dedicated waiting area, and a spacious conference room—ideal for professional services, agencies, or corporate use. Additional highlights include: On-site parking lot approx. 9 spaces, two shared restrooms conveniently located on the main level, Prominent roadside signage offering exceptional exposure on a high-traffic Main Street corridor, Ample flexibility to suit a wide range of business types and tenant configurations Whether you’re looking to fully lease all five units for maximum cash flow or occupy one space while generating income from the others, this property presents a compelling opportunity to secure a high-performing commercial asset in a premier location.

Listing Status:

Active

Date Added:

April 14, 2026

Data Last Updated:

August 10, 2026 at 8:18PM

Listing Office:

Keller Williams Realty WNY : 716-832-3300

Listing Agent:

Anthony Dubreville : 716-374-2594

Contact:

716-374-2594

MLS ID:

B1671172

Interior

• Basement: Full
• Flooring: LinoleumOtherSee RemarksVinyl
• A/C:
• Heating: GasBaseboard
• Fireplace: Fireplaces: 0

Exterior

• Parking: On SiteParking spaces: 9

Construction

• Roofing: FlatMembraneRubber
• General: BrickBlock2

Location

• Originating MLS: NYS_B
• School District: Amherst
• County: Erie

Lot

• Zoning: TI-2.5142289-068-170-0004-041-000

Utilities

• Utilities: Electricity ConnectedSewer Connected
• Sewer: Public Sewer

Financial

• Source: NYS_B