4053 MARKET ST, Philadelphia, PA 19104

Property Description

Prime University City Commercial Opportunity at 40th & Market! Offering +/- 2,200 SF of premium ground-floor space with high-visibility Market Street frontage. Situated in a high-density, mixed-use building directly adjacent to the University of Pennsylvania and Drexel University campuses. PROPERTY HIGHLIGHTS: (1) Zoning: CMX-4 (High-Density Commercial Mixed-Use) allows for a wide array of uses by-right. (2) Foot Traffic: Exceptional pedestrian volume driven by tens of thousands of nearby students, healthcare professionals, and residents. (3) Transit-Oriented: Immediate, steps-away access to the SEPTA Market-Frankford Line (40th St Station), trolley lines, and bus routes. (4) Layout: Flexible, open layout adaptable for diverse builds. Features prominent storefront exposure along Market Street. IDEAL USES: Perfect for Medical/Dental Clinics, Physical Therapy, Professional Office, Daycare, Educational Services, Specialty Retail, Cafés, Tech Showrooms, Wellness Centers, Daycare, or Restaurant. LOCATION ADJACENCIES: Unbeatable location in Philadelphia’s most dynamic innovation district, minutes from Penn Medicine, Children’s Hospital of Philadelphia (CHOP), and major science/tech hubs. Leverage the massive daytime population and unparalleled visibility in one of the city's most rapidly growing commercial corridors. Schedule your tour today!

Listing Status:

Active

Data Last Updated:

June 24, 2026 at 2:19AM

Listing Office:

Keller Williams Main Line : 6105200100

Listing Agent:

Lily L Wu : 6107616426

MLS ID:

PAPH2631170

Interior

• A/C: Central A/C
• Heating: Forced AirNatural Gas
• Disability Feature: Ramp - Main LevelLevel Entry - Main2+ Access Exits

Construction

• General: Masonry

Location

• Originating MLS: BRIGHT_MAIN
• School District: PHILADELPHIA CITY
• County: PHILADELPHIA-PA

Lot

• Zoning: CMX4871065350
• Current Use: Other

Utilities

• Water: Public
• Sewer: Public Sewer

Financial

• Source: BRIGHT_MAIN